Futurama never hesitates to kill a character to pluck viewers emotions. But maybe death isn't so bad compared to these guys.
As an alien Quantum Lichen, Cobb must keep a bag over his head at all times, lest humans look upon him and have their life force drained. A blind, lonely life.
An alternate reality where no one can see, smell, hear, or taste. To be fair, they're probably used to it.
The original cast of "Stark Trek"
Crash landing on Omega 3 after being banished from Earth in the 23rd century, the original cast of Star Trek (minus Leonard Nimoy) was forced to participate in a Trek Convention for over 700 years.
Robot Santa's Workers
Jolly Junction residents have little to do since everyone is naughty and no one gets toys. Meaning paychecks and food are few and far between. Starvation is on top of having a murderous psychopath for a boss.